Microwave Assisted Organic Synthesis

Microwave Assisted Organic Synthesis

Microwave-assisted Domino Reaction in Organic Synthesis

The fields of combinatorial and automated medicinal chemistry have emerged to meet the increasing requirement of new compounds for drug discovery, where speed is of the essence (Loupy, 2002). In this regard, domino (or tandem, or cascade) reactions where “two or more bond-forming transformations take place under the same reaction conditions without adding additional reagents and catalysts, and ...

A microreactor for microwave-assisted capillary (continuous flow) organic synthesis.

A capillary-based flow system has been developed for conducting microscale organic synthesis with the aid of microwave irradiation. The capillary internal diameter investigated ranged from 200 to 1200 mum, while the flow rate was varied between 2 and 40 muL/min, which corresponds to the sample being irradiated approximately 4 min. Other parameters investigated include reaction concentration and...

Microwave-assisted synthesis of molybdenum oxide nanoparticles

This paper focused on a simple approach for synthesis of molybdenum oxide (MoO3) nanoparticles and reports a facile route for synthesis of such nanoparticles, using microwave irradiation as a homogenous and powerful source of heating, using ethylene glycol as the solvent and heating medium. For more investigations, besides microwave heating, the obtained solutions were also treated by conventio...

Machine-Assisted Organic Synthesis.

In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors. In the rapidly changing, multivariant environment of the research laboratory, equipment needs to be modular to accommodate high and low temperatures and pressures, enzymes, multiphase systems, slurries...